|
KMID : 0931320150150040236
|
|
대한상부위장관.헬리코박터학회지
2015 Volume.15 No. 4 p.236 ~ p.242
|
|
|
Trend in the Eradication Rates of Helicobacter pylori Infection in the Last 8 Years in Daegu: A Single Center Experience
|
|
김시혜:Kim Si-Hye
정진태:Jung Jin-Tae/권중구:Kwon Joong-Goo/김은영:Kim Eun-Young/강선미:Kang Sun-Mi/송정은:Song Jeong-Eun
|
|
|
Abstract
|
|
|
Background/Aims: Helicobacter pylori eradication rates achieved by first-line triple treatment with proton pump inhibitor (PPI), clarithromycin, and amoxicillin have decreased to 70∼85%, in part due to increasing antimicrobial resistance. This study evaluated the trend in H. pylori eradication rates during the most recent 8 years in Daegu, Korea and analyzed different clinical factors between success group and failure group of H. pylori eradication.
Materials and Methods: This was a retrospective study at a single institution. A total of 768 H. pylori-positive patients who received one or two weeks of first-line triple regimens were included between January 2007 and October 2014.
Results: The overall H. pylori eradication rate was 86%. The eradication rate from years 2007 to 2014 was 80.5%, 89.4%, 95.6%, 85.5%, 87.9%, 75.8%, 83.3%, and 85.8%, respectively (P=0.027). There was no significant difference in the eradication rate among various PPIs (P=0.358). In addition, there were no significant difference of clinical factors between success and failure group of H. pylori eradication.
Conclusions: The eradication rates of first-line triple therapy for H. pylori over 8 years were 75.8∼95.6%. No significant difference in clinical factors were noted between success and failure group of H. pylori eradication. Triple therapy may be a useful regimen for H. pylori eradication in Daegu.
|
|
|
KEYWORD
|
|
|
Helicobacter pylori, Disease eradication
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|